Animals in Research

At Lilly, we know we have both an ethical and a scientific responsibility toward animals used in research. That’s why we have adopted the international recognised standard,“3Rs” when it comes to our principles of animal care and use:

  • Replacement: using other research methods where possible, such as in vitro (test tube) or in silico (computer based).
  • Reduction: designing experiments to use as few animals as possible.
  • Refinement: modifying experimental techniques to eliminate or minimize pain or distress.

Lilly maintains the highest standards of animal care. All Lilly-owned animal testing facilities worldwide are accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) and are subject to external review and inspection. We comply fully with all Regulations and Guidance, including European Directive 63/2010 and the Animals (Scientific Procedures) Act 1986.

All Lilly employees and third parties who work with animals in research are required to comply with all applicable laws, regulations, codes of conduct and standards regarding the care and use of animals as well as Lilly’s Animal Care and Use Principles, which are aligned to the 3Rs; even when these principles are more stringent than applicable local laws. Any staff involved with working with animals must be appropriately trained and qualified to ensure that they are competent, that they are aware of humane and ethical issues, and that they demonstrate respect for all research animals.

In 2014, Lilly UK were one of the first organisations to sign the Concordat on Openness in Animal Research. This declaration includes four commitments to increasing transparency and set out how organisations will be more open about the ways in which animals are used in scientific, medical and veterinary research in the UK.

Further information about Lilly’s global approach to animal research can be found at